Adjusted and ideal body weight calculator
Ideal body weight (Devine method) and 40% adjusted body weight
Ideal body weight according to the 1974 Devine formula (50 kg + 2.3 kg per inch in height over 5 feet) correlates with the clearance of some drugs.1
The adjusted body weight formula presented here assumes that 40% of the excess body weight (above ideal body weight) is lean mass. Many oncologists make use of this adjusted body weight formula to dose chemotherapies in obese patients.2
Note that Clinical Practice Guidelines from the American Society of Clinical Oncology recommend the use of actual body weight (rather than adjusted body weight or ideal body weight) for the dosing of chemotherapy in obesity.3
- Pai MP and Paloucek FP. The origin of the “ideal” body weight equations. Ann Pharmacother. 2000; 34: 1066-9.
- Thompson LA, Lawson AP, Sutphin SD, Steinke D and Adams VR. Description of current practices of empiric chemotherapy dose adjustment in obese adult patients. J Oncol Pract 2010; 6: 141-5.
- Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ and Hryniuk WM. Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2012; 30: 1553-61.